Gene description for Cct4
Gene name chaperonin containing TCP1 subunit 4
Gene symbol Cct4
Other names/aliases 2610204B21Rik
A45
Cctd
Species Mus musculus
 Experiment description of studies that identified Cct4 in Myeloid-derived suppressor cells

1
Experiment ID678
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 29951053   
OrganismMus musculus
Experiment descriptionImmunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.
AuthorsZör M, Zhao K, Kutlu N, Bauer N, Provaznik J, Hackert T, Schnör M.
Journal name Front Immunol
Publication year2018
SampleMyeloid-derived suppressor cells
Sample nameIn-vitro- Alopecia areata affected C3H/HeJ mice BMC derived
Isolation/purification methodsUltracentrifugation
Density gradient centrifugation
Flotation densityNot provided
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

2
Experiment ID679
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 29951053   
OrganismMus musculus
Experiment descriptionImmunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.
AuthorsZör M, Zhao K, Kutlu N, Bauer N, Provaznik J, Hackert T, Schnör M.
Journal name Front Immunol
Publication year2018
SampleMyeloid-derived suppressor cells
Sample nameEx-vivo- Alopecia areata affected C3H/HeJ mice
Isolation/purification methodsUltracentrifugation
Density gradient centrifugation
Flotation densityNot provided
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

3
Experiment ID1126
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24295599   
OrganismMus musculus
Experiment descriptionExosomes from myeloid-derived suppressor cells carry biologically active proteins.
AuthorsBurke M, Choksawangkarn W, Edwards N, Ostrand-Rosenberg S, Fenselau C.
Journal name J Proteome Res
Publication year2014
SampleMyeloid-derived suppressor cells
Sample nameConventional MDSC's-BALB/c mice injected with 4T1 cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140063: EV-METRIC:71%

4
Experiment ID1127
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24295599   
OrganismMus musculus
Experiment descriptionExosomes from myeloid-derived suppressor cells carry biologically active proteins.
AuthorsBurke M, Choksawangkarn W, Edwards N, Ostrand-Rosenberg S, Fenselau C.
Journal name J Proteome Res
Publication year2014
SampleMyeloid-derived suppressor cells
Sample nameInflammatory MDSC's-BALB/c mice injected with 4T1 cells expressing IL-1.
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140063: EV-METRIC:71%

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